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Korean Circ J. 2012 May;42(5):345-348. English. Case Report.
Rahman A , Islam AM , Husnayen S .
Department of Cardiology, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh.
Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh.
Department of Cardiology, Zia Heart Foundation Hospital and Research Institute, Dinajpur, Bangladesh.

Deep vein thrombosis (DVT) is a common condition that is often under-diagnosed. Acquired or hereditary defects of coagulation or a combination of these defects may facilitate the development of DVT. Recurrent DVT, a positive family history or unusual presentation may warrant investigation for hereditary thrombophilia. Investigations are best when conducted at least one month after completion of a course of anticoagulant therapy. Most patients are managed with heparin in the acute stage overlapped by warfarin. The case presented here describes a 40-year old man undergoing three episodes of DVT. Investigations revealed protein C and protein S deficiency. Protein C, protein S and antithrombin deficiency either singly or in combination, are relatively common causes of hereditary thrombophilia. The case presented here serves as a reminder of the need to look into the underlying cause of venous thromboembolism.

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