Kasabach-Merritt syndrome is rare disorder which consists of hemangioma and thromobocytopenia occurring in infatns. Two cases of giant hemanioma with thrombocytopenia and anemia are reported with review of literures. It is postulated that the abnormalities resulted from intravascular coagulation within the hemangioma. Those patients were managed with prednisolone administration, blood transfusion and compression with the elastic bandage over the hemangioma. Following the conservative therapy the hemangioma regressed and the platelet and the erythrocyte returned to normal.