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J Korean Soc Med Ultrasound. 2003 Dec;22(4):233-238. Korean. Original Article.
Kim EK , Kwak JY , You JK , Park CS , Chung WY , Yang WI , Oh KK .
Department of Diagnostic Radiology, Research Institute of Radiological Science. Severance Hospital, Yonsei University College of Medicine, Korea. ekkim@yumc.yonsei.ac.kr
Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Korea.
Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Korea.
Abstract

PURPOSE: To evaluate the efficacy of ultrasound-guided percutaneous core-needle biopsy in establishing histopathologic diagnoses of cervical lymphadenopathy. MATERIALS AND METHODS: Seventy nine patients with cervical lymphadenopathy without a history of malignancy or recent infection underwent ultrasound-guided core-needle biopsies. Lymph node tissues were obtained by 2 to 4 times of freehand core-needle biopsy technique using a 7.5-12 MHz ultrasound transducer and a short-excursion (12 mm), spring-loaded automated gun with an 16-gauge cutting needle. We evaluated diagnostic yields of biopsies and related complication. RESULTS: Histologic diagnoses were conclusive in 73 cases (92.4%) including 57 benign causes (24 cases of tuberculous lymphadenitis, 19 cases of reactive hyperplasia, 14 cases of Kikuchi Disease and 2 cases of nonspecific lymphadenitis) and 12 malignancies (8 cases of metastatic lymphadenopathy, 7 cases of lymphoma). In 5 of 7 patients with lymphoma, histologic subclassification was established with obtained tissue to guide treatment. No complications were seen after biopsy. CONCLUSION: Ultrasound-guided core-needle biopsy of cervical lymphadenopathy is a safe, minimally invasive alternative to surgical biopsy, enabling a histologic diagnosis for treatment planning in the majority of cases.

Copyright © 2019. Korean Association of Medical Journal Editors.