Tuberculosis is caused by bacteria belonging to the Mycobacterium tuberculosis complex. Tuberculosis usually affects lung, although in about one-third of cases other organs are involved. Most of M. tuberculosis are drug susceptible strains, so infected patients are curable in virtually all cases. If untreated, the disease may be fatal within 5 years in more than half of cases and can be transmitted to others. We experienced a case of bone tuberculosis which was diagnosed by AFB stain in bone marrow aspirated filter biopsy. The patient was diagnosed later as a disseminated tuberculosis in which M. tuberculosis involved lung, lumbar spines, bone and brain.