Tuberculosis can be superimposed on many hematologic disorders. Numerous hematologic abnormalities are also associated with tuberculosis, especially disseminated form. With this controversy, when the patient has tuberculosis and hematologic abnormalities, it is important to differentiate tuberculosis from primary hematologic disorder. Especially, most patients with tuberculosis and pancytopenia have been reported to have underlying hematologic disorder. We present two rare cases in which patients with myelodysplastic syndrome had disseminated tuberculosis involving the bone marrow.