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J Korean Neurosurg Soc. 1989 Jan;18(1):59-65. Korean. Original Article.
Chung YK , Lim CS , Chung HS , Lee HG , Lee KC , Chu JW .
Department of Neurosurgery, College of Medicine, Korea University, Seoul, Korea.

9 patients with spasticity of cerebral or spinal cord origin have been maintained for upto 2 months with intermittent bolus spinal intrathecal infusion of baclofen. Prior to treatment, all of patients had severe spastiuity in extremties & had frequent & extensive spontaneous spasms, all of which greatly interfered with their activities of daily living. Oral antispasmodic medications were ineffective. Within days of intrathecal baclofen infusion, the muscle tone was reduced remarkable & spasms were eliminated. The greatest benefit to the patients were improvement in activities of daily living & better sleep due to reduced spasms. Complications were not observed.

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