Cystic disease of the liver is observed with increasing frequency because of the common use of computed tomography and ultrasonography. Hepatic cyst does not present particular symptoms. However, depending on its size and location, symptoms like abdominal distension, or pressure effects on adjacent organs including bile ducts causing intermittent jaundice could appear. Patients with hepatic cyst usually show no elevation of liver enzyme, bilirubin, or liver function tests. Jaundice usually can occur in the patients when the cyst becomes large enough to cause exrtahepatic blocking of bile duct. We receotly experienced a 57-year old female complaining of generalized pruritus, which was diagnosed as non-parasitic liver cyst with obstructive jaundice. The diagnosis was confirmed by abdominal US, CT, ERCP and operation. Unroofing of hepatic cyst was performed, and 3 months later, she was asyrnptomatic and total bilirubin was normalized. We report this case with a review of the relevant literatures.