Journal Browser Advanced Search Help
Journal Browser Advanced search HELP
Korean J Pathol. 2012 Jun;46(3):292-296. English. Case Report.
Kang Y , Jung W , Do IG , Lee EJ , Lee MH , Kim KM , Choi J .
Department of Pathology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. kkmkys@skku.edu
Department of Biology, Cornell University, Ithaca, NY, USA.
Abstract

Plexiform angiomyxoid myofibroblastic tumor (PAMT) of the stomach is a recently recognized entity. Because of its rarity, only 22 cases have been reported in the English-language literature and most of these are single case reports. We report two cases of gastric PAMT. The tumor cells were bland and plexiform arranged in a myxoid stroma, which was positive for alcian blue. Immunohistochemically, the tumor cells were positive for smooth muscle actin, but negative for c-kit, CD34, desmin, S-100 protein, epithelial membrane antigen, neurofilament, and protein kinase C-theta. Mutation analyses for exon 9, 11, 13, and 17 of KIT genes and 12, 14, and 18 of the platelet-derived growth factor receptor alpha (PDGFRA) genes were performed and the tumors were wild-type for mutation.

Copyright © 2019. Korean Association of Medical Journal Editors.