The record of radiation therapy cases during a five-ear period at the University of Michigan Hospitals has been analyzed. Of a total of 73 Aden carcinoma of prostate, the majority belonged to Stage B and C which represented 49 and 20 cases, respectively. The mortality rate after irradiation was clearly related to the tumor stage. Local irradiation resulted in 88% of the local control of well-ifferentiated Aden carcinomas. Stage C cases had 50% mortality, whereas that of Stage B patients was 14%. Results of this study are in general agreement with previous data in terms of the local disease control after irradiation and provide a basis for conservative radiotherapy regimen as an approach in the treatment of localized prostatic carcinomas.