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J Korean Radiol Soc. 2008 Jun;58(6):561-569. Korean. Original Article. https://doi.org/10.3348/jkrs.2008.58.6.561
Yoo O , Jung GS , Ko JH , Han BH , Shin DH .
Department of Radiology, Gospel Hospital, College of Medicine, Kosin University, Korea. gsjung@medimail.co.kr
Department of Radiology, Masan Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
Department of Internal Medicine, Gospel Hospital, College of Medicine, Kosin University, Korea.
Department of General Surgery, Gospel Hospital, College of Medicine, Kosin University, Korea.
Abstract

PURPOSE: We wanted to determine the technical and clinical efficacy of placing a self-expandable PTFE-covered nitinol stent for the management of inoperable malignant biliary obstruction. MATERIALS AND METHODS: Thirty six patients with inoperable malignant biliary obstructions were treated by placement of self-expandable PTFE-covered nitinol stents (S & G Biotech Corporation, Seongnam, Korea). Clinical evaluation was done with assessment of the serum bilirubin and alkaline phosphatase levels, which were measured before and after stent placement within 1 week, at 1 month and at 3 months. The patient survival rate and stent patency rate were calculated with performing Kaplan-Meier survival analysis. RESULTS: Successful stent placement was achieved in all the patients without procedure-related complication. Pancreatitis as an early complication occurred in two cases. The serum bilirubin and alkaline phosphatase levels were significantly decreased after the procedure. During the follow-up, recurrent obstructive jaundice occurred in six cases; stent migration occurred in four cases and tumor overgrowth occurred in two cases. The survival rates were 97%, 80%, 67% and 59% at 1, 3, 6 and 9 months, respectively. The stent patency rates were 96%, 92%, 86% and 86% at 1, 3, 6 and 9 months, respectively. CONCLUSION: Self-expandable PTFE-covered nitinol stent placement seems to be technically feasible and effective for the palliative treatment of malignant biliary obstruction.

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