PURPOSE: To evaluate the relative image qualities obtained at magnetic resonance cholangiopancreatography (MRCP) turbo spin-echo (SSTSE) sequence and the three-dimensional turbo spin-echo (3D TSE) sequence with the sensitivity encoding (SENSE) technique. MATERIALS AND METHODS: Forty patients with suspected hepatic and extrahepatic diseases underwent MRCP using the SSTSE sequence and the 3D TSE sequence with the SENSE technique. Three radiologists scored and compared the quality of images of anatomic structures in the hepatopancreatic biliary system, and then directly compared the quality of the images obtained using the two sequences in each set of cases. RESULTS: For visualization of the intrahepatic bile duct, the cystic duct, the common bile duct, and the pancreatic duct, MRCP images obtained using the 3D TSE sequence with the SENSE technique were better than those obtained using the SSTSE sequence, though for the intrahepatic bile duct and common bile duct only, were these differences statistically significant (p<0.05). Quality was best for images of the common bile duct (87.5% for SSTSE and 97.5 % for 3D TSE with the SENSE technique). For the pancreatic and cystic duct, however, 52.5% and 10% of SSTSE images, respectively, and 57.5% and 32.5% of 3D TSE images, respectively, provided optimal image quality. In direct comparison, 3D TSE images obtained using the SENSE technique were better in 27 cases (67.5%), both images were equivocal in five cases (12.5%), and SSTSE images were better in eight cases (20%). These differences were statistically significant (p<0.05). CONCLUSION: For the visualization of anatomic structures in the hepatopancreatic biliary system, the 3D TSE sequence with the SENSE technique was better than the SSTSE sequence. For evaluation of the pancreatic and cystic duct, however, both techniques have their limitations and require further development.