Polycystic diseases is defined as a heritable disorder with diffuse involvement of both kidneys. The term"Polycystic disease"comprises at least two separate, genetically different diseases-one with an onset typically inchildhood (infantile polycystic disases) and the other with an onset typically in adulthood(adult polycysticdisease). Adult polycystic kidney disease is the most common form of cystic kidney diseases in humans.Ultrasonography is a very useful noninvasive diagnostic modality in the patient with clinically suspected renaldiseases as well as screening test. 14 cases of ultrasonography in patient with polycystic kidney were reviewed.All cases show unilateral or bilateral enlarged kidneys. 7 cases reveal kidneys and liver replaced multiple cystsof varing size. Screening ultrasonography for a familial tree is reported.