We experienced one case of anesthesia for liver transplantation in a 14 year old girl with Wilson's disease. The liver was donated from a patient with a brain tumor who was diagnosed as brain death. We monitored blood pressure, heart rate, cardiac output, pulmonary capillary wedge pressure, systemic vascular resistance, arterial pH, arterial PCO2, serum potassium, ionized calcium, glucose, and blood coagulation states including platelet count, prothrombin time, activated partial thromboplastin time and coagulation factor assay. We used isoflurane and nitrous oxide as the main inhalation anesthetics. The operation was performed without serious problem. The patient became conscious three hours after the operation.