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J Rheum Dis. 2012 Dec;19(6):364-368. Korean. Case Report. https://doi.org/10.4078/jrd.2012.19.6.364
Lee SJ , Kim EH , Kim YS , Song JE , Chung SJ , Lee CK , Chang MH , Kang JG , Choi YJ , Park SM , Lee CH .
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea. chanheell@paran.com
Department of Surgery, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
Department of Pathology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
Department of Radiology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
Abstract

Sarcoidosis is a multi-systemic granulomatous disease of unknown cause, which most commonly involves lung, skin, eye, liver and lymph nodes. Herein, we report a case of sarcoidosis presented with massive ascites. A 47-year-old male patient visited our hospital with symptoms of general weakness and weight loss from past 4 months. Abdomen computed tomography showed multiple lymphadenopathy and hepatosplenomegaly. Lymph node biopsy demonstrated non-caseating granulomas. After biopsy, development of massive uncontrolled ascites was noted. Liver biopsy showed non-cirrhotic hepatic and portal fibrosis and omental biopsy showed submesothelial diffuse fibrosis and focal chronic inflammation, which were suggestive of hepatic and peritoneal involvement in sarcoidosis. Ascites was controlled after subsequent treatment with corticosteroids and methotrexate.

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