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J Rheum Dis. 2012 Dec;19(6):359-363. Korean. Case Report. https://doi.org/10.4078/jrd.2012.19.6.359
Choi EY , Kim JO , Kim YS , Yoon HJ , Jun JB , Sung YK .
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. sungyk@hanyang.ac.kr
Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.
Abstract

We report a 67-year-old woman who developed Pneumocystis jirovecii pneumonia (PJP) as a complication of treatment with immunosuppressant, such as methotrexate and leflunomide, for rheumatoid arthritis. She had mild fever and non-productive cough, but there was neither symptoms of dyspnea nor typical X-ray findings at initial presentation. However, rapid progression on a chest X-ray, respiratory symptoms and findings of high-resolution chest computed tomography in a few days suggested a possibility of PJP infection. A polymerase chain reaction-based detection of Pneumocystis jirovecii in induced sputum allowed us an early diagnosis of PJP. Through a preemptive treatment with Trimethoprim-sulfamethoxazole, she fully recovered from PJP.

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