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J Korean Soc Endocrinol. 2005 Oct;20(5):519-523. Korean. Case Report.
Kang SG , Bae JO , Lee EY , Lim SM , Cho SK , Kim JH , Song SK .
Division of Endocrinology and Metabolism, Department of Internal Medicine, Presbyterian Medical Center, Cheonju, Korea.

Methimazole is a widely used and generally well-tolerated antithyroid agent. Adverse reactions occur in 1~5% of patients taking methimazole medication, but these are most commonly transient, benign leukopenia and a skin rash. Severe cholestatic jaundice, combined with agranulocytosis, has been known as a rare complication. Herein, a case of methimazole induced cholestatic jaundice, with agranulocytosis, is reported.

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