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J Korean Soc Endocrinol. 2001 Feb;16(1):115-122. Korean. Case Report.
Park YJ , Lee MK , Hahm JR , Do JH , Heo ST , Kim JS , Min YK , Lee MS , Kim KW , Han JH .
Division of Endocrinology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University of Medical School, Seoul, Korea.
Department of Pathology, Samsung Medical Center, Sungkyunkwan University of Medical School, Seoul, Korea.
Departmeut of Internal Medicine, College of Medicine, Gyeongsang National University, Chinju, Korea.
Abstract

Primary neuroendocrine carcinoma of the thymus (formerly known as thymic carcinoids) are unusual tumors that account for 5% of all anterior mediastinal neoplasms. Thymic neuroendocrine carcinomas exhibit a much more aggressive behavior than those originating from other foregut locations and are associated with the ectopic ACTH syndrome in 38% of cases. Patients having a thymic neuroendocrine carcinoma usually present with symptoms such as chest tightness, dyspnea, a palpable neck mass and sometimes a weight gain. We report on 2 patients with thymic neuroendocrine carcinoma who showed different clinical manifestations each other. One presented with a typical. Cushingoid appearance and the other had symptoms of fatigue and weight loss which is a common symptom of malignant tumors.

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