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Korean J Hepatol. 2010 Jun;16(2):176-181. Korean. Case Report.
Hwang S , Kim DY , Kim M , Chon YE , Lee HJ , Park YN , Park JY , Ahn SH , Han KH , Chon CY .
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. dyk1025@yuhs.ac
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract

Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal portal hypertension. Among various hepatoportal disorders, noncirrhotic portal hypertension conditions such as idiopathic portal hypertension (IPH) are considered to have a close relation with PVT. PVT is known to have several predisposing conditions, including infection, malignancies, and coagulation disorders. There is growing interest and recognition that deficiencies in proteins C and S are associated with a hypercoagulable state. These deficiencies are regarded as key factors of systemic hypercoagulability and recurrent venous thromboembolism. We report the case of a 19-year-old male diagnosed as IPH with PVT and combined deficiencies in proteins C and S.

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