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Tuberc Respir Dis. 2008 Dec;65(6):541-545. Korean. Case Report.
Oh MN , Cho MJ , Baek HK , Cho KS , Kang JH , Kim Y , Kwak JY .
Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.

Hypersensitivity pneumonitis (HP) is an immunologically-mediated disease resulting from repeated exposure to sensitizing agents, such as organic dusts or chemicals. Isocyanate is a volatile and highly reactive chemical that is extensively used in the manufacturing of automobiles, upholstery, and polyurethane foam. Occupational respiratory diseases associated with isocyanate, such as bronchial asthma, are well-known. It is thought that HP is one of the rare diseases induced by isocyanate with a very low frequency worldwide. We report a case of HP in an automobile painting sprayer which appeared to be associated with isocyanate.

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