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Clin Psychopharmacol Neurosci. 2014 Dec;12(3):218-221. English. Original Article. https://doi.org/10.9758/cpn.2014.12.3.218
Hirao K .
Department of Occupational Therapy, School of Health Science and Social Welfare, Kibi International University, Okayama, Japan. hirao-k@kiui.ac.jp
Abstract

OBJECTIVE: The relationship between paranoia symptoms and underlying prefrontal cortex mechanisms among healthy subjects was analyzed using near-infrared spectroscopy. METHODS: Seventy-eight healthy subjects were assessed for paranoia symptoms using the Japanese version of the Paranoia Checklist. Changes in hemoglobin concentrations were assessed using 2-channel near-infrared spectroscopy on the surface of the prefrontal cortex while subjects performed a verbal fluency test. RESULTS: Changes in the concentration of oxygenated hemoglobin in the prefrontal cortex during a verbal fluency test did not correlate with the Japanese version of the Paranoia Checklist. CONCLUSION: Our findings show that the symptoms of paranoia do not negatively affect the prefrontal cortex function among healthy subjects.

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