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J Korean Bone Joint Tumor Soc. 2012 Jun;18(1):45-49. Korean. Case Report.
Cheon GJ , Choe JG , Chae IJ , Lee DH , Song SH , Kim MJ , Park JH .
Department of Orthopedic Surgery, Korea University Hospital, Seoul, Korea.
Department of Nuclear Medicine, Korea University Hospital, Seoul, Korea.

Skip lesion is not uncommon feature in osteosarcoma and considered to be importantly associated with poor prognosis factor, and thus, should be excised with the main mass. The accurate pre-operative evaluation of the intramedullary extent of osteosarcoma is essential, because it determines the level of bone resection. Among the reliable detection methods, bone scan has a drawback of high rate of false negative results and regional MRI has a difficulty to cover the whole involved lesions without clinical suspicion. The authors report a case of osteosarcoma of the distal femur with a proximal skip lesion that was not detected by either regional MR imaging or by bone scan, but which was visualized by FDG-PET/CT.

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