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Anesth Pain Med. 2011 Apr;6(2):160-163. English. Case Report.
Lee HM , Kim SD , Kim OR , Jee DL .
Department of Anesthesia and Pain Medicine, Yeungnam University, Daegu, Korea.
Department of Neurosurgery, School of Medicine, Yeungnam University, Daegu, Korea.

The trans-sphenoidal resection of a recurred pituitary tumor was performed in a 42 years old man under general anesthesia with propofol and remifentanil. Neither massive bleeding nor hypotension was observed intraoperatively, but bradycardia was sustained over five hours. The patient did not suffer from hypertriglyceridemia and there was no evidence of drug toxicity or vigorous intervention during the surgery, however hyperamylasemia was observed one day after the surgery. It is presumed that vagal stimulation by propofol and remifentanil infusion might induce bradycardia and abnormal pancreatic enzyme secretion consequently.

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