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J Korean Acad Periodontol. 2008 Jun;38(2):191-198. Korean. Original Article.
Jeong JY , Sohn JY , Chai KJ , Kim ST , Chung SM , Lee IS , Cho KS , Kim CK , Choi SH .
Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration, Korea.
Dentium Co., Korea.
Institute of Physics & Applied Physics, and Atomic-scale Surface Science Research Center, Yonsei University, Korea.

PURPOSE: Guided bone regeneration(GBR) has emerged as a treatment in the management of osseous defects associated with dental implants. But several studies have reported different degrees of success of guided bone regeneration, depending upon the type of barrier selected, presence or absence of an underlying graft material, types of graft material, feasibility of technique, and clinician's preference. The aim of the present study was to evaluate bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs. MATERIAL AND METHODS: Standardized buccal dehiscence defects(3x5 mm) were surgically 2 Mongrel dog's mandibles, each 8 SLA surface, 8 anodizing surface implants. Each buccal dehiscence defect received flap surgery only(no treatment, control), Cytoflex(R) membrane only, Resolut XT(R) membrane only, Resolut XT(R)+Osteon(TM). Animals were sacrificed at 8 weeks postsurgery and block sections were harvested for histologic analysis. RESULTS: All experimental group resulted in higher bone formation than control. Resolut XT(R)+Osteon(TM) group resulted appeared highest defect resolution. There was no difference between SLA and anodizing surface, nonresorbable and resorbable membrane. CONCLUSION: GBR results in rapid and clinically relevant bone closure on dehiscence defects of the dental implants.

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