Journal Browser Advanced Search Help
Journal Browser Advanced search HELP
J Clin Neurol. 2008 Sep;4(3):134-137. English. Case Report. https://doi.org/10.3988/jcn.2008.4.3.134
Ye BS , Cho YJ , Jang SH , Lee BI , Heo K , Jung HH , Chang JW , Kim SH .
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. kheo@yuhs.ac
Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract

BACKGROUND: Neurocutaneous melanosis (NCM) is a rare neurocutaneous syndrome characterized by the presence of multiple congenital melanocytic nevi (CMN) and the proliferation of melanocytes in the central nervous system, usually involving the leptomeninges. Chronic partial epilepsy as a sole manifestation is rare in NCM. CASE REPORT: A 32-year-old man suffering from chronic partial epilepsy presented with multiple CMN on his trunk and scalp. Brain MRI demonstrated a focal lesion in the right amygdala that was consistent with interictal epileptiform discharges in the right temporal region on electroencephalography (EEG). An anterior temporal lobectomy was performed, and the pathology investigation revealed numerous melanophages in the amygdala. The patient was seizure-free after surgery. CONCLUSIONS: We report a patient with NCM presenting as chronic partial epilepsy who was successfully treated by anterior temporal lobectomy.

Copyright © 2019. Korean Association of Medical Journal Editors.