Journal Browser Advanced Search Help
Journal Browser Advanced search HELP
Korean J Obes. 2009 Dec;18(4):131-137. Korean. Original Article.
Ahn KY , Choi YS , Lee DW , Kim KY , Kim JH , Sung HN , Choi KM , Kim SM , Lee CB .
Department of Family Medicine, Korea University Medical Center Guro Hospital, Korea.
Department of Family Medicine, Korea University Medical Center Ansan Hospital, Korea.
Division of Endocrinology & Metabolism, Korea University Medical Center Guro Hospital, Korea.
Department of Endocrinology and Metabolism, Guri Hospital, Hanyang University School of Medicine, Korea. lekang@hanyang.ac.kr
Abstract

BACKGROUND: Low grade inflammation has been proposed as a pathophysiologic mechanism of obesity. Thus, we sought to determine the relation of C-reactive protein to obesity in Korean children. METHODS: We selected 585 children aged 9 years in Seoul. Anthropometric measurements and fasting blood samples were collected and body mass index (BMI) was calculated as weight/height2. We measured high-sensitivity CRP (hs-CRP), glucose (FBS), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and triglyceride (TG). RESULTS: Hs-CRP concentration was positively correlated with weight, BMI, waist circumference and negatively correlated with HDL-C. On multivariate analysis, these variables emerged as independent determinants of hs-CRP concentration. CONCLUSION: Obesity is associated with higher hs-CRP concentration. These findings suggest a state of subclinical inflammation in obese children.

Copyright © 2019. Korean Association of Medical Journal Editors.