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Korean J Pediatr Gastroenterol Nutr. 2004 Mar;7(1):87-91. Korean. Case Report. https://doi.org/10.5223/kjpgn.2004.7.1.87
Choi WJ , Lee BY , Lee HJ , Oh HK , Hwang JB .
Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea. pedgi@korea.com
Department of Diagnostic Radiology, Keimyung University School of Medicine, Daegu, Korea.
Department of Pathology, Keimyung University School of Medicine, Daegu, Korea.
Abstract

Herein, the case of a 5-year-old boy with cytomegalovirus-induced Menetrier's disease, with peripheral eosinophilia, presenting with abdominal pain and vomiting, followed by generalized edema, is reported. The initial laboratory findings, hypoalbuminemia and peripheral eosinophilia were noted, with no evidence of renal, hepatic, cardiac or allergic diseases. Gastrofiberscopy was performed under the suspicion of eosinophilic gastroenteritis with protein losing gastropathy. The gastrofiberscopy showed the characteristic features of giant hypertrophy of the gastric rugae, with large quantities of adherent gelatinous material on the gastric fundus and body. The histological findings revealed foveolar hyperplasia, compatible with Menetrier's disease, with massive eosinophilic infiltrations. The presence of cytomegalovirus infection was identified by serology and confirmed by urine PCR. His symptoms, gastrofiberscopic findings and peripheral eosinophilia resolved spontaneously, and he has remained well for 10 months.

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