PURPOSE: To evaluate the results of conservative treatment of zone I, II 5th metatarsal base fracture. MATERIALS AND METHODS: Between May 2004 and June 2010, a total of 58 patients of zone I, II 5th metatarsal base fractures were included in this study. The mean length of follow-up was 13.5 months (12~36 months). All of the patients were treated with full-weight-bearing short leg cast immobilization for 4 weeks and wooden sole shoes for 4 weeks. The results were evaluated about the radiographic union, the midfoot scale of American Orthopaedic Foot and Ankle Society (AOFAS), the tenderness on fracture site and other complications. RESULTS: All patients were able to return to their prior levels of activity. The mean time for union as shown on radiographs was 45.5 days, and the mean midfoot scale of AOFAS was 99.7 points. There were no nonunions or refractures during the follow-up. CONCLUSION: The conservative treatment with full-weight-bearing short leg cast and wooden sole shoes seems to give good results for zone I, II 5th metatarsal base fracture.