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Korean J Biol Psychiatry. 2018 Aug;25(3):79-87. Korean. Original Article.
Hong HS , Jeong JE , Cho H , Kwak SM , Choi MR , Choi JS , Choi SW , Kim DJ .
Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. kdj922@catholic.ac.kr
Addiction Laboratory, Department of Psychiatry, College of Medicine, The Catholic of University of Korea, Seoul, Korea.
Department of Psychology, Korea University, Seoul, Korea.
Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
Truemind Mental Health Clinic, Seoul, Korea.
Abstract

Objectives

Internet gaming disorder (IGD) is known to be related to stress and the serotonin-transporter-linked polymorphic region (5-HTTLPR) that is known to be associated with stress and has been studied to affect various psychiatric illness outbreaks. We tried to examine the relationship between stress, 5-HTTLPR and IGD.

Methods

A total of 59 participants with IGD, diagnosed according to the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria and 67 normal controls (NC) were enrolled. The IGD group and the NC were compared using chisquare test and independent sample t-test, and logistic regression analysis was used to examine the relationship between stress, the 5-HTTLPR, and IGD.

Results

The mean scores for anxiety, impulsivity and stress were significantly higher in the IGD group than in the NC. In addition, there was a significant association between stress and IGD [odds ratio (OR) = 1.172, 95% confidence interval (CI) = 1.008–1.362].

Conclusions

This study showed that stress would affect IGD. Therefore, the evaluation and management of stress should be included in the diagnosis and treatment of IGD.

Copyright © 2019. Korean Association of Medical Journal Editors.