Clin Pediatr Hematol Oncol. 2013 Apr;20(1):75-78. English. Case Report.
Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun-gun, Korea. email@example.com
Department of Pediatrics, Shenzen People's Hospital, China.
Department of Neurosurgery, Chonnam National University Hwasun Hospital, Hwasun-gun, Korea.
Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.
The growing teratoma syndrome (GTS) is defined as the development of mature low-grade elements in the absence of a recurrent non-germinomatous germ-cell tumor (NGGCT) after partial response to multimodal treatment. It is uncommon and may occur in intracranial NGGCTs. Here, we report that a 7-year-old boy with intracranial NGGCT presented with precocious puberty and developed growing teratoma syndrome only 2 weeks after the first cycle of chemotherapy.