Infection is one of the most feared complications in vascular surgery, especially when it involves the aortoiliac segment. There are many controversies in the treatment of aortoiliac graft infection with varying results reported. The author treated 2 cases of graft infection after an aortobiiliac bypass. These patients had an abdominal aortic aneurysm with aortoenteric fistula before or after the bypass surgery. Both developed graft infection within about 1 year after the first operation. One was treated with an extra-anatomic bypass after complete removal of the infected graft; and the other was treated with a re-aortobifemoral bypass with bilateral femoral vein graft. Both patients showed no recurrence of infection nor limb loss.