Epidermoid tumors of the central nervous system are infrequent(2%) and can occur congenitally or iatrogenically. Since Choremis et. al. reported intradural-extramedullary epidermoid tumor after repeated lumbar puncture, several cases have been reported. We experienced a case of epidermoid inclusion cyst after single lumbar puncture in a 7-year-old boy and report the clinical and radiologic findings with relevant literatures.