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J Korean Soc Transplant. 2013 Sep;27(3):128-131. English. Case Report. https://doi.org/10.4285/jkstn.2013.27.3.128
Choi Y , Lee H , Yun Y , Lee Y , Hwang E , Jeong H , Kim BS .
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. docbsk@yuhs.ac
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract

Antiphospholipid syndrome nephropathy (APSN) is well documented in the literature as the renal involvement of the antiphospholipid syndrome (APS). A review of literature also shows that among antiphospholipid antibodies, lupus anticoagulant (LA) positivity is recognized as the strongest risk factor for APSN. In addition, APSN is also known to be associated with a poor functional outcome in the first posttransplant year. Therefore, it is a general belief that renal transplantation may be life threatening in APS patients. Furthermore, the presence of LA at the time of transplantation is particularly associated with a high rate of allograft APSN and the consequent poor transplantation outcomes. Here, we report the case that thrombotic acute kidney injury due to APSN after kidney transplantation can be successfully treated if anticoagulation therapy is timely applied with a prompt diagnosis.

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