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J Bacteriol Virol. 2009 Jun;39(2):97-102. English. Original Article.
Jeong MR , Kim HY , Cha JD .
Research Center of Bioactive Materials, Chonbuk National University, Jeonju, Korea.
Department of Dental Hygiene, College of Natural Sciences, Dongeui University, Busan, Korea.
Oral Cancer Research Institute, College of Dentistry, Yonsei University, Seoul, Korea.

Ficus carica L. (fig) belongs to the mulberry tree (Moraceae) which is one of the oldest fruits in the world. It has been used as a digestion promoter and a cure for ulcerative inflammation and eruption in Korea. The present study investigated the antimicrobial activity of methanol (MeOH) extract of figs against oral bacteria. The MeOH extract (MICs, 0.156 to 5 mg/ml; MBCs, 0.313 to 5 mg/ml) showed a strong antibacterial activity against oral bacteria. The combination effects of MeOH extract with ampicillin or gentamicin were synergistic against oral bacteria. We suggest that figs could be employed as a natural antibacterial agent in oral care products.

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