OBJECTIVES: To investigate the related factors on fatigue symptoms among married working women. METHODS: Data was analyzed from a cross-sectional survey of 902 married working women. Information was obtained about fatigue symptoms, sociodemographics, health behaviors, and job-related characteristics. Multiple regression tested the related factors on fatigue symptoms in married working women. RESULTS: Fatigue was more common in office working women than in manufacture working women. Mean fatigue symptom was significantly higher in office working than in manufacture working women(p=0.002). In a multiple regression analysis, fatigue was associated with educational level, alcohol drinking state, stress, and overtime work in a multiple regression analysis(p<0.001). CONCLUSIONS: Our findings suggest that fatigue is affected by job-related factor like overtime work with educational level, alcohol drinking state, or stress. Further research will be needed to establish preventive strategies for controlling the negative effects of fatigue on health stats of married working women.