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J Asthma Allergy Clin Immunol. 2002 Jun;22(2):487-493. Korean. Original Article.
Cho JH , Kim HJ , Moon JY , Jang SM , Kim HJ , Bae SW , Kim CW , Sunwoo IN , Cho SH , Hong CS .
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract

Churg-Strauss syndrome is one of idiopathic, systemic necrotizing vasculitis characterized by a history of asthma or allergic rhinitis, eosinophilia of peripheral blood and variable symptoms of systemic vasculitis. There have been several recent case reports of Churg-Strauss syndrome in association with leukotriene modifier therapy when oral corticosteroids were withdrawn in asthmatic patients. We report a case of a 31-year-old man with steroid-dependent asthma who developed Churg-Strauss syndrome after 9 months of steroid withdrawal period, while he was receiving leukotriene modifier (Pranlukast).

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