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Chonnam Med J. 2001 Sep;37(3):293-298. Korean. Case Report.
Kim KS , Yu YK , Lim SC , Na KJ , Kim YH , Choi YD , Kim KS , Kim YC , Park KO .
Department of Internal Medicine, Chonnam National University Medical School, Kwangju, Korea.
Department of Thorasic Surgery, Chonnam National University Medical School, Kwangju, Korea.
Department of Diagnostic Radiology, Chonnam National University Medical School, Kwangju, Korea.
Department of Pathology, Chonnam National University Medical School, Kwangju, Korea.
Department of Anatomic Pathology, Kwangju Christian Hospital, Kwangju, Korea.
Chonnam National University Research Institute of Medical Sciences, Kwangju, Korea.
Abstract

Pulmonary eosinophilic granuloma, a rare form of Langerhans cell histiocytosis confined to lung, is a granulomatous disorder of the lung of unknown cause. Eosinophilic granuloma is clinically suspected in the presence of diffuse pulmonary infiltrate and bony involvement. The radiologic findings of lung are variable according to the stage of disease. Therefore pathologic diagnosis is essential for confirmative diagnosis. Pathologically it is characterized by proliferation of Langerhans cells mixed with lymphocytes, plasma cells and eosinophils. Over 90% of patients are cigarette smokers, and it is rarely reported in non-smokers. We report two cases of eosinophilic granuloma manifested as spontaneous pneumothorax in two young patients. Both were active cigarette smokers and subsequently confirmed as eosinophilic granuloma with open lung biopsy and Video associated thoracoscopic surgery (VATS).

Copyright © 2019. Korean Association of Medical Journal Editors.