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Korean J Pediatr. 2014 Dec;57(12):514-519. English. Review. https://doi.org/10.3345/kjp.2014.57.12.514
Han SB , Cho B , Kang JH .
Department of Pediatrics, The Catholic University of Korea College of Medicine, Seoul, Korea. chobinkr@catholic.ac.kr
The Vaccine Bio Research Institute, The Catholic University of Korea College of Medicine, Seoul, Korea.
The Catholic Blood and Marrow Transplantation Center, The Catholic University of Korea College of Medicine, Seoul, Korea.
Abstract

Hemorrhagic cystitis is a common stem cell transplantation-related complication. The incidence of early-onset hemorrhagic cystitis, which is related to the pretransplant conditioning regimen, has decreased with the concomitant use of mesna and hyperhydration. However, late-onset hemorrhagic cystitis, which is usually caused by the BK virus, continues to develop. Although the BK virus is the most common pathogenic microorganism of poststem cell transplantation late-onset hemorrhagic cystitis, pediatricians outside the hemato-oncology and nephrology specialties tend to be unfamiliar with hemorrhagic cystitis and the BK virus. Moreover, no standard guidelines for the early diagnosis and treatment of BK virus-associated hemorrhagic cystitis after stem cell transplantation have been established. Here, we briefly introduce poststem cell transplantation BK virus-associated hemorrhagic cystitis.

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