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Korean J Pediatr. 2011 Jul;54(7):292-297. English. Original Article.
Oh JE , Jung J , Kim HS , Hong YM , Yoo JH , Song YW , Jung JW , Kim NS , Noh CI .
Department of Pediatrics, Ewha Womans University School of Medicine, Seoul, Korea.
Department of Radiology, Ewha Womans University School of Medicine, Seoul, Korea.
Department of Pediatrics, Inje University College of Medicine, Busan, Korea.
Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
Department of Pediatrics, Han Yang University College of Medicine, Seoul, Korea.
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.

PURPOSE: Our study aimed to evaluated sex differences in clinical features of obese high school students. METHODS: One hundred three obese high school students (body mass index [BMI]> or =85th percentile) and 51 control students (BMI<85th percentile) were enrolled in this study. Anthropometric measurements were performed. Fasting serum glucose, insulin, aspartate aminotransferase, alanine aminotransferase, total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and high-sensitive C-reactive protein were measured. Abdominal fat thickness, degree of fatty liver, and carotid intima-media thickness were measured by ultrasound. RESULTS: In control and obese groups, waist circumference was significantly longer in boys but body fat mass was significantly higher in girls. In the control group, total cholesterol and LDL-C were higher in girls. In the obese group, however, aspartate aminotransferase, alanine aminotransferase and triglyceride were higher and HDL-C was lower in boys. Preperitoneal fat thickness was significantly higher in obese girls. In obese group, the degree of fatty liver was significantly higher in boys. Carotid intima-media thickness was not significantly different between boys and girls. CONCLUSION: Obese adolescents had distinguishable sex differences in body measurements, metabolic abnormalities, abdominal fat thickness and fatty liver. We can infer that these characteristics may extend into adult obesity.

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