PURPOSE: To assess the regional wall motion of the left ventricle in patients with diastolic overloaded lesions of congenital heart diseases with centerline analysis and radial method. METHODS: This study included 96 children with congenital heart diseases admitted to Kyungpook National University Hospital from January 1998 to December 2002 who received left ventriculograms. The evaluation of the regional wall motion of the left ventricle was done on review mode of 30-degree elongated right anterior oblique projection of left ventriculogram by using cardiac analysis program of the DXC Hiline Digital System(GER, Paris, France). RESULTS: Compared with the control group, the left ventricular regional wall motions of patients with right ventricular diastolic overload were significantly decreased at the anterolateral portion and increased at the diaphragmatic portion with the centerline analysis method, but no differences were noted with the radial method. CONCLUSION: We confirmed left ventricular regional wall motion abnormalities in patients with right ventricular diastolic overload lesions of congenital heart diseases with the centerline method in spite of normal ejection fraction.