OBJECTIVE: The purpose was to investigate the characteristics of oropharyngeal dysphagia and videofluoroscopic study (VFSS) findings in esophageal diseases. METHOD: We retrospectively reviewed the clinical characteristics and VFSS findings in thirteen patients with esophageal cancer and stricture. Videofluoroscopic parameters of oral, pharyngeal, and esophageal phases were measured. Patients were divided into three groups according to their diseases: Group A, esophageal cancer with esophagectomy (5 patients); Group B, esophageal cancer with non-operative treatment (3 patients); and Group C, esophageal stricture with surgical treatment (5 patients). RESULTS: Group A had vocal cord palsy (VCP) after esophagectomy, and all patients showed poor laryngeal closure and aspiration during swallowing. Group B received radiation therapy prior to VFSS and showed poor laryngeal closure and high pharyngeal residue with aspiration during and after swallowing. Group C received esophagectomy with anastomosis of lower gastrointestinal tract (stomach, jejunum, colon). Most had VCP and showed high pharyngeal residue, stricture of upper esophageal sphincter, and poor oral control with aspiration during and after swallowing. CONCLUSION: Characteristics of dysphagia on VFSS were poor laryngeal closure in operated esophageal cancer patients. In patients of non-operated esophageal cancer and esophageal stricture, high pharyngeal residue and poor laryngeal closure were characterized.