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J Korean Acad Rehabil Med. 1997 Oct;21(5):1039-1044. Korean. Case Report.
Kim MS , Kim HS , Hwang CM , Ahn KH .
Department of Rehabilitation Medicine, Kyung Hee University College of Medicine, Korea.
Department of Rehabilitation Medicine, Kyung Hee Pundang Cha Hospital, Korea.

Mononeuritis multiplex may be a manifestation of systemic vasculitis or of other illnesses such as sarcoidosis, diabetes, lymphoma, and AIDS. Anti-neutrophil cytoplasmic autoantibody(ANCA) is a serologic marker for pauci-immune crescentic glomerulonephritis and systemic necrotizing arteritis, including polyarteritis nodosa, Wegener's granulomatosis and so-called ANCA-associated vasculitis. We report a case of mononeuritis multiplex due to ANCA associated vasculitis. A 46-year-old female visited hospital because of peripheral edema, pain and dyspnea. We diagnosed neuropathy associated with vasculitis by electrophysiologic study, sural nerve biopsy and angiography. The patient was treated with prednisolone and cyclophosphamide. Her symptoms and signs improved and her ANCA test was converted from positive to negative.

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