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Korean J Lab Med. 2011 Oct;31(4):298-301. English. Case Report. https://doi.org/10.3343/kjlm.2011.31.4.298
Roh KH , Lee CK , Sohn JW , Song W , Yong D , Lee K .
Department of Laboratory Medicine, Korea University College of Medicine, Seoul, Korea.
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Department of Laboratory Medicine, Hallym University College of Medicine, Seoul, Korea. swonkeun@hallym.or.kr
Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.
Abstract

Carbapenem-resistant Klebsiella pneumoniae isolates producing K. pneumoniae carbapenemases (KPC) were first reported in the USA in 2001, and since then, this infection has been reported in Europe, Israel, South America, and China. In Korea, the first KPC-2-producing K. pneumoniae sequence type (ST) 11 strain was detected in 2010. We report the case of a patient with a urinary tract infection caused by KPC-2-producing K. pneumoniae. This is the second report of a KPC-2-producing K. pneumoniae infection in Korea, but the multilocus sequence type was ST258. The KPC-2-producing isolate was resistant to all tested beta-lactams (including imipenem and meropenem), amikacin, tobramycin, ciprofloxacin, levofloxacin, and trimethoprim-sulfamethoxazole, but was susceptible to gentamicin, colistin, polymyxin B, and tigecycline. The KPC-2-producing isolate was negative to phenotypic extended-spectrum beta-lactamase (ESBL) and AmpC detection tests and positive to modified Hodge test and carbapenemase inhibition test with aminophenylboronic acid.

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