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J Korean Surg Soc. 2010 Sep;79(3):196-201. English. Original Article.
Yu W , Chung HY .
Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.

PURPOSE: We evaluated the clinical implication of Resection A surgery retrospectively to identify whether quality of surgery can be used as a selection factor for adjuvant therapy in patients with gastric cancer. METHODS: Prognosis of 902 patients with gastric cancer who underwent Resection A surgery was evaluated. RESULTS: Among all discharged patients, 77 patients (8.5%) died of recurrent disease, 55 patients (6.1%) died without recurrent disease. Five-year survival rate of all discharged patients was 91.6% and 10-year survival rate 87.1%. Statistically significant prognostic factors were depth of invasion (P<0.001), lymph node metastasis (P<0.001), stage (P<0.001), tumor location (P=0.036) and size (P=0.001), extent of gastric resection (P<0.001), and chemotherapy (P<0.001) on univariate analyses. However, depth of invasion (P=0.001), lymph node metastasis (P<0.001), and total gastrectomy (P<0.001) emerged as statistically significant poor prognostic factor on a multivariate analysis. Adjuvant chemotherapy did not increase the survival rate of patients after Resection A surgery, even in patients with stage II disease. CONCLUSION: In selecting the patients for adjuvant therapy, both the stage of gastric cancer and the quality of surgery should be considered.

Copyright © 2019. Korean Association of Medical Journal Editors.