Colonoscopic evaluation has revolutionized the management of colorectal disorders, of which colorectal neoplasia is the most important. Experience with 2000 consecutive colonoscopies was reviewed to determine their clinical significance. The symptoms that patients complained about were anal bleeding, abdominal pain, diarrhea, and constipation. Colonic polyps, colon cancer, and ulcerative colitis were diagnosed by colonoscopy. Colonic polyps were the most common pathology for anal bleeding and constipation. Ulcerative colitis was the most common pathology for diarrhea. Intestinal tuberculosis was the most common pathology for abdominal pain. Colon cancer was the most common pathology for tenesmus. Lymphoid hyperplasia was the most common pathology in patients under 10. Ulcerative colitis was the most common pathology in patients in their 3rd or 4th decade. Colonic polyp was the most common pathology in patients in their 5th, 6th, or 7th decade. Colon cancer was the most common pathology in patients in their of 8th or 9th decade. A colonoscopic polypectomy was performed in 49.5% of the colonoscopies, and an open polypectomy was done in 2.7%. There were no surgical complications from the colonoscopies. As a result of this study, it is concluded that total colonoscopic examination should be performed in patients over 40 who complain about rectal bleeding and tenesmus. To avoid complications and give proper management, it is recommended that colonoscopy be performed by a surgeon.