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Korean J Gastrointest Endosc. 2008 Jan;36(1):48-51. Korean. Case Report.
Bang BW , Jeong S , Kim CH , Lee DH , Kim JM , Lee JI , Lee JW , Kwon KS , Kim HG , Shin YW , Kim YS .
Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. inos@inha.ac.kr
Department of Pathology, Inha University College of Medicine, Incheon, Korea.
Abstract

A ganglioneuroma is a benign tumor composed of ganglion cells, nerve fibers, and supporting cells that originates from the neural crest. An occurrence of a ganglioneuroma is mainly along the pathway of the sympathetic chain. However, it is rare to find the lesion in the gastrointestinal tract. A ganglioneuroma of the gastrointestinal tract appears to involve predominantly the colon and rectum, but rarely involves the upper gastrointestinal tract. An intestinal ganglioneuroma is divided into three subgroups: a polypoid ganglioneuroma, ganglioneuromatous polyposis, and diffuse ganglioneuromatosis. A polypoid ganglioneuroma is not associated with systemic disease. However, ganglioneuromatous polyposis and diffuse ganglioneuromatosis are highly associated with systemic diseases. A 33-year-old woman who had no specific family history visited our institution with a complaint of abdominal discomfort. A single polyp was found incidentally in the descending colon during a colonoscopy and it was treated by snare polypectomy. The patient had no associated systemic disease and histology of the polyp revealed a ganglioneuroma. We report a patient with a polypoid ganglioneuroma of the colon.

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