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Korean J Gastrointest Endosc. 2003 Oct;27(4):211-215. Korean. Case Report.
Lee JH , Lee OJ , Min HJ , Kang DY , Moon IG , Lee KD , Kim HJ , Kim TH , Jung WT .
Department of Internal Medicine, Gyeongsang National University College of Medicine, Jinju, Korea.

Candida species are the most common cause of all cases of infectious esophagitis, and Candida albicans is the main causative organism of these infections. Candida glabrata has been considered a relatively nonpathogenic saprophyte of the normal flora of healthy individuals, rarely causing serious infection in human. However, following the widespread and increased use of broad-spectrum antibiotics and immunosuppressive therapy, the frequency of infections caused by C. glabrata has increased significantly. C. glabrata is of special importance because C. glabrata infections are associated with a highest mortality rate and resistant to azole antifungal agents, especially fluconazole. We report a case of C. glabrata esophagitis resistant to fluconazole but treated effectively with amphotericin B.

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