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Korean J Gastrointest Endosc. 2003 Mar;26(3):146-149. Korean. Case Report.
Hwang YY , Jo YK , Cha JM , Kim KH , Na IH , Lee DH , Ha HS , Kim SH , Song CS .
Department of Internal Medicine, Samsun Hospital, Busan, Korea.

Although Crohn's disease is usually found in the ileum and colon, it can be located in the whole gastrointestinal tract from the oral cavity to the anus. The frequency of gastroduodenal Crohn's disease is rare and is reported to range between 0.5% and 4.0% in Crohn's disease. And when Crohn's disease does involve the upper gastrointestinal tract, there is nearly always concomitant disease in the small bowel and colon. Very rarely, isolated Crohn's disease of the stomach and duodenum may occur. Definite diagnosis requires histologic confirmation, however, endoscopic biopsies often fail to reveal granuloma. Thus, if absence of definite histologic findings, combining clinical, radiologic and endoscopic findings suggest this condition. We experienced a first case of Crohn's disease confined to stomach and reported with review of the literature.

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