Esophageal tuberculosis is a rare form of adult tuberculosis, even in countries with a high incidence of tuberculosis. Secondary esophageal tuberculosis is more common than primary tuberculosis and may result from direct extension from adjacent mediastinal or hilar lymph nodes with tuberculosis or from extension from the pharynx or larynx. Clinical symptoms related to esophageal tuberculosis are dysphagia, mild fever, hematemesis and melena. Because esophageal tuberculosis has clinical symptoms and radiological appearance similar to that of esophageal malignancy, esophageal tuberculosis should be considered in the differential diagnosis of esophageal malignancy. In this report, we describe three patients with esophageal tuberculosis, diagnosed by endoscopy with biopsy and responed well to antituberculosis chemotherapy.