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J Korean Child Neurol Soc. 2000 Dec;8(2):309-313. Korean. Case Report.
Kim SY , Lee IG , Choi BJ , Kim YH , Chung SY , Kim HK , Whang KT .
Department of Pediatrics, College of Medicine, Catholic University of Korea, Seoul, Korea.

The antiphospholipid syndrome is a multisystemic disorder comprising of venous and arterial thrombotic events, recurrent unexplained fetal losses, moderate thrombocytopenia, and a high frequency of neurologic events with laboratory findings of a positive lupus anticoagulant test or anticardiolipin antibody. It may occur in association with other disorders, particularly autoimmune diseases, in which case it is referred to as secondary antiphospholipid syndrome. But when it occurs without obvious underlying disease, it is primary antiphospholipid syndrome. We report a case of primary antiphospholipid syndrome in a 5 year old female child who had a cerebrovascular attack, moderate thrombocytopenia and splenomegaly.

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