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J Korean Rheum Assoc. 2010 Mar;17(1):16-22. Korean. Review. https://doi.org/10.4078/jkra.2010.17.1.16
Kang SW .
Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea. kangsw@cnuh.co.kr
Abstract

Vitamins and their metabolites are essential for many physiological processes including immune response. In addition to regulating calcium homeostasis, vitamin D exerts various effects on cells of the immune system, such as macrophages, dendritic cells as well as, B and T cells. Low vitamin D levels are found in patients with autoimmune diseases, which suggest a potential role of vitamin D in autoimmunity. In this review, we discuss the roles of vitamin D in modulating immune responses and the clinical potential of vitamin D metabolites for preventing and treating inflammatory and autoimmune diseases.

Copyright © 2019. Korean Association of Medical Journal Editors.