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J Korean Rheum Assoc. 2010 Mar;17(1):16-22. Korean. Review.
Kang SW .
Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

Vitamins and their metabolites are essential for many physiological processes including immune response. In addition to regulating calcium homeostasis, vitamin D exerts various effects on cells of the immune system, such as macrophages, dendritic cells as well as, B and T cells. Low vitamin D levels are found in patients with autoimmune diseases, which suggest a potential role of vitamin D in autoimmunity. In this review, we discuss the roles of vitamin D in modulating immune responses and the clinical potential of vitamin D metabolites for preventing and treating inflammatory and autoimmune diseases.

Copyright © 2019. Korean Association of Medical Journal Editors.